Computed Tomography of Lethal Midline Granuloma

In order to clarify the CT findings oflethal midline granuloma (LMG) diagnosed clinically or histopathologically , the authors retrospectively analyzed 12 patients who were seen at Kyungpook National University Hospital from February 1985 to August 1989. CT showed nasal mucosal thickening and/or soft tissue mass (9 cases) , spreading of the lesions along the facial subcutaneous fat plane (8 cases), invasion into the paranasal sinuses (5 cases), bone destruction (5 cases) , nasopharyngeal mass lesion (2 cases), and extension of the lesion into the infratemporal fossa (1 case). In spite of the fact that CT does not make definitive diagnosis of LMG , it permits evaluation of the extent of the lesion , detection of the combined lesion, differential diagnosis , and close monitoring of its evolution under treatment.